Operations

Crafft – Children’s Radius Acute Fracture Fixation Trial. A multi-centre prospective randomized non- inferiority trial of surgical reduction versus non-surgical casting for displaced distal radius fractures in children.

FRUITI – World Hip Trauma Evaluation – a framework for clinical trials for fragility hip fracture in those aged 60 and over

PART – The clinical and cost-effectiveness of elective primary total knee replacement with PAtellar Resurfacing compared to selective patellar resurfacing. A pragmatic multicentre randomised controlled Trial with blinding

PETS – Examining the benefit of graduated compression stockings in the Prevention of vEnous Thromboembolism in low-risk Surgical patients: a multicentre cluster randomised controlled trial

POP-1 – The clinical benefits and cost effectiveness and safety of haematopoietic interventions for patients with anaemia following major emergency surgery

PRESSURE3 – Pressure ulcer prevention 3: A randomised clinical trial assessing early heel specific adjunct devices for heel pressure ulcer prevention in people with a fractured hip

RAPSODI – Reverse or Anatomical replacement for Painful Shoulder Osteoarthritis, Differences between Interventions (RAPSODI): a multi-centre, pragmatic, parallel group, superiority randomised controlled trial

REPPORT – REcurrent Patellar dislocation: Personalised therapy or OpeRative Treatment?

Sunflower – A randomised controlled trial to establish the clinical and cost effectiveness of expectant management versus pre-operative imaging with Magnetic Resonance Cholangiopancreatography (MRCP) in patients with symptomatic gallstones undergoing laparoscopic cholecystectomy at low or moderate risk of common bile duct stones

Vapor – Volatile organic compound assessment in pancreatic ductal adenocarcinoma –  Repeated

PANDOS – Pain and opioids after surgery

POPPY – Patient reported outcomes, postoperative pain and pain relief after day case surgery

PQIP – Improving perioperative care through the use of quality data: patient study of the perioperative quality improvement programme

VITAL – Volatile vs Total intravenous Anaesthesia for major non-cardiac surgery: A pragmatic randomised triaL

Distal Radius Acute Fracture Trial 3 – Cast versus Splint (DRAFT3-CASP): a randomised non-inferiority trial comparing clinical and cost-effectiveness of a standard care cast versus removable splint for adults with a distal radius fracture that does not require manipulation

REACH – Randomised Evaluation of rehabilitation and Acute proximal Humerus fracture: a multi-centre, non-inferiority, randomised trial to compare the clinical and cost-effectiveness of a self-directed rehabilitation programme versus physiotherapist-supervised rehabilitation (usual care) for adults with a proximal humerus fracture

Thromboprophylaxis in Lower Limb Immobilisation (TiLLI) – a multicentre study comprising two linked open label phase III randomised controlled trials evaluating the effectiveness and cost effectiveness of different methods of pharmacological prophylaxis for patients with temporary lower limb immobilisation.